产品货号：
Z16423
中文名称：
GADD153/DDIT3抗体
英文名称：
Anti-GADD153/DDIT3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GADD153/DDIT3 Antibody |
| 指标别名 | CEBPZ;CHOP;CHOP 10;CHOP;GADD153;DDIT 3;DDIT3;GADD153 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | DDIT3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human DDIT3 recombinant protein (Position:M1-A169). |
| 实际分子量 | 29KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DNA damage-inducible transcript 3,also known as C/EBP homologous protein (CHOP),is a pro-apoptotictranscription factor that is encoded by the DDIT3 gene.It is mapped to 12q13.3.This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors.The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members,such as C/EBP and LAP (liver activator protein),and preventing their DNA binding activity.The protein is implicated in adipogenesis and erythropoiesis,is activated by endoplasmic reticulum stress,and promotes apoptosis.Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma.Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. |
| Uniprot ID | P35638 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | DNA damage inducible transcript 3 |
| 蛋白名全称 | DNA damage-inducible transcript 3 protein |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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